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The Role of Testosterone in Women's Mental Health and Menopause


Testosterone, commonly associated with male health, is also an important hormone in women. Although present in lower amounts than in men, testosterone plays a crucial role in women’s mental and physical health. Understanding its influence on mood, cognition, and overall mental well-being can provide insights into how hormonal imbalances might contribute to psychological issues and guide appropriate treatments for women.

Testosterone's Influence on Mental Health in Women

Mood Regulation: Testosterone has a significant impact on mood and emotional well-being in women. Adequate levels of testosterone are associated with positive mood, increased energy, and overall feelings of well-being. Conversely, low levels of testosterone can lead to mood swings, irritability, and a higher risk of depression.

Cognitive Function: Testosterone affects cognitive abilities, including memory, attention, and spatial abilities. Research suggests that optimal levels of testosterone can enhance cognitive performance, while both low and excessively high levels might impair cognitive function.

Stress and Anxiety: Testosterone helps in managing stress and reducing anxiety levels. It influences the body's response to stress by interacting with cortisol, the stress hormone. Balanced testosterone levels can mitigate the effects of cortisol, promoting a calmer and more resilient mental state.

Motivation and Drive: Testosterone is linked to motivation, ambition, and drive. It enhances competitiveness and the pursuit of goals, which can contribute to a sense of purpose and achievement. Low testosterone levels might result in a lack of motivation and decreased interest in activities that were once enjoyable.

Testosterone Imbalances and Mental Health Conditions in Women

Low Testosterone (Hypogonadism):

  • Symptoms: Depression, fatigue, irritability, and decreased libido.

  • Causes: Aging, medical conditions, certain medications, and lifestyle factors.

  • Treatment: Hormone replacement therapy (HRT), lifestyle changes (such as exercise and diet), and addressing underlying medical issues.

High Testosterone:

  • Symptoms: Aggressiveness, impulsivity, and mood swings.

  • Causes: Polycystic ovary syndrome (PCOS), certain medical conditions, and genetic factors.

  • Treatment: Medications to reduce testosterone levels, lifestyle modifications, and addressing the underlying causes.

Recognising the Signs of Testosterone Imbalance

Identifying the signs of testosterone imbalance is essential for timely intervention. Common signs in women include:

  • Persistent fatigue

  • Mood swings and irritability

  • Decreased libido

  • Depression and anxiety

  • Cognitive difficulties (e.g., memory problems, difficulty concentrating)

  • Changes in motivation and drive

Treatments and Management

Lifestyle Changes:

  • Exercise: Regular physical activity, especially resistance training, can help maintain healthy testosterone levels.

  • Diet: A balanced diet rich in healthy fats, lean proteins, and whole grains supports hormonal health.

  • Sleep: Ensuring adequate and quality sleep is crucial for maintaining optimal testosterone levels.

Medical Treatments:

  • Hormone Replacement Therapy (HRT): Used to treat low testosterone levels, Testosterone HRT can be administered through transdermal gels.

  • Medications: In cases of high testosterone, medications might be prescribed to lower levels.

Alternative Treatments:

  • Herbal Supplements: Some supplements, like ashwagandha and fenugreek, are believed to support healthy testosterone levels. It’s essential to consult a healthcare provider before starting any supplement.

  • Stress Management: Techniques such as mindfulness, meditation, and yoga can help manage stress and support hormonal balance.

Testosterone and the menopause

Female testosterone replacement therapy (TRT) is a medical treatment designed to address low levels of testosterone in women.

Options for female testosterone replacement- unfortunately we do not have a female specific licensed testosterone product. we often prescribe very small doses of the testosterone replacement products available in the U.K. Testosterone in the menopause is not licensed in the U.K which is why it is often not available via your GP.

Available brands at The Menopause Specialists

  1. Testogel

  2. Tostran

  3. Androfeme

Tostran an option for female testosterone replacement
Tostran - Testosterone in the menopause


Testosterone plays a vital role in women's mental health, influencing mood, cognition, stress management, and motivation. Understanding the effects of testosterone imbalances can help in recognising symptoms and seeking appropriate treatment. Whether through lifestyle changes, medical interventions, or alternative treatments, maintaining balanced testosterone levels is key to promoting mental well-being in women. As research continues, a deeper understanding of testosterone's impact on women's mental health will hopefully lead to more effective treatments and support systems.

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